Artificial Heart Research Paper

Artificial Heart Research Paper-57
Artificial heart devices work to increase blood flow and to sustain life for end-stage heart failure patients.These devices may completely replace or assist the diseased native heart.

Artificial heart devices work to increase blood flow and to sustain life for end-stage heart failure patients.These devices may completely replace or assist the diseased native heart.

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It is distinct from a cardiac pump, which is an external device used to provide the functions of both the heart and the lungs.

Thus, the cardiac pump need not be connected to both blood circuits.

A small but innovative group of researchers experimented with device mechanics, biomaterials, implant tolerance in the body, and other issues.

They battled persistent technical problems such as blood clotting in the device, power source issues, pump malfunctions, and more.

Frazier has been a pioneer in the treatment of severe heart failure and in the fields of heart transplantation and artificial devices that may be used either to substitute for or assist the pumping action of the human heart. Frazier continued experimental work toward developing an implantable left ventricular assist device (LVAD) to aid the failing heart, which he first implanted in 1986 with the Heart Mate I; this device has become the most widely used implantable LVAD in the world. Frazier implanted the first successful continuous-flow total artificial heart, using two second generation Heart Mate II LVADs to replace a patient’s failing heart.

These are life-sustaining devices that do a remarkable thing: they alter the usual course of events that when a person’s heart failed, that person died.Also, a cardiac pump is only suitable for use not longer than a few hours, while for the artificial heart the current record is 17 months.This synthetic replacement for an organic mammalian heart (usually human), remains one of the long-sought goals of modern medicine.In other cases, patients battled infections, bleeding, strokes and device malfunction after their implants. Artificial heart research teams published their device challenges and setbacks in the medical literature.Journalists reported on various experimental devices that had been implanted in patients, often including color photographs from the operating room. Nonetheless, NIH continued to support multiple device approaches, bolstered by the confidence and optimism of researchers that a viable mechanical heart would be forthcoming.Pulsed cavitation ultrasound can be used to remotely soften human degenerative calcified biosprosthetic valves and significantly improve the valve opening function, according to a new study. More than 40 million people worldwide are blind, and many of them reach this condition after many years of slow and progressive retinal degeneration. A study of human gut bacteria -- known as the gut microbiome -- suggests that high blood pressure with depression may be a completely different disease than high blood pressure without depression. Scientists have identified the regional character to Plasmodium falciparum across Africa.Malaria, infecting 219 million individuals in 2017, remains a threat to public health and regional stability. A team of researchers evaluated whether it would be cost-effective to combine several medications into a single 'cardiovascular polypill' for patients who have had a previous heart attack or stroke, ...How and why did this problematic technology continue to be developed for so long?I argue that desirability rather than the feasibility or practicality of artificial hearts drove the development of this technology.Variable characterizations of success sustained the hope that viable devices would be developed, despite discouraging patient results.It was an imperfect technology, but one that became ‘good enough’ in a medical culture shaped by aggressive surgical fixes and a reluctance to accept limits.


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